At least 500 people have been killed in an alleged Israeli strike on a hospital in Gaza, according to Palestinian officials.
However, Israeli Army spokesperson said the cause of the incident was not known and the Army was looking into the details.
A United Nations-run school in Central Gaza where 4,000 people are sheltering was also hit during an Israeli air strike, killing at least six people.
“No place is safe in Gaza anymore, not even United Nations Relief and Works Agency for Palestine Refugees in the Near East (UNRWA) facilities,” Philippe Lazzarini, UNRWA Commissioner-General said.
Earlier, the Israeli military insisted it was not targeting civilians, adding: “When we see a Hamas target, we will go after it.”
At least 600,000 people have fled the northern Gaza Strip for the south after Israeli military warnings.
Israel has blocked supplies of food, water, fuel, and electricity since the deadly Hamas attacks on October 7 but denies there is a humanitarian crisis.
The United States President, Joe Biden, will visit Israel on Wednesday to hear about its plans for a ground attack in Gaza.